faebugz
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@wolfen
Thought you might be interested to read this, lavender had a scraping done and a cytological report that I just got back today- TL;DR it's looking like cancer:
"Site or Source:
Lateral thoracic lesion
Microscopic Description:
The slides are moderately cellular and have captured variably sized clusters of slightly cuboidal (epithelial) cells occasionally exfoliating with a scant amount of magenta mucinous extracellular material. The cells show modest cohesion and contain moderate amounts of basophilic cytoplasm, commonly with a light sprinkling of a very fine magenta granules. There nuclear to cytoplasmic ratio is moderate to high, and nuclei are round/ovoid to irregular with smooth chromatin and usually inapparent nucleoli. There is nuclear molding present in some clusters and anisokaryosis of approximately 2.5X. Erythrocytes are rare in the background.
Microscopic Interpretation:
FAVOUR EPITHELIAL TUMOR, See comment
Comment:
There is no evidence of inflammation, or any fungal agents found on cytology. Instead I am seeing a proliferation of modestly cohesive cells which I am interpreting as epithelial, and most likely neoplastic. I am not finding much literature regarding axolotl neoplasia, but epithelioma and neuroepithelioma are recognized in this species. The cells in question contain cytoplasmic granules resembling mast cells, and although mast cell tumor is also reported in axolotls, I do not believe the cells are mast cells based on the degree of cohesion. I considered whether this could be a regenerative blastema, but presumably the patient is not missing any limbs? Overall based on this sampling I suspect a neoplastic rather than infectious process; histopathology can be advised, if possible, and I would be interested in hearing of any follow-up information for this patient"
My vet is away until the 1st, so I'm just going to hang tight and do everything I can to minimize stress until then. He's pretty confident he will be able to treat it, thankfully. When he gets back we will do a biopsy just to get a 100% confirmation of what we're dealing with, and then formulate a plan from there.
Luckily lavender doesn't appear to be ill and is in good spirits despite being caught daily for baths and swabs. Mama mia this is an ordeal
Thought you might be interested to read this, lavender had a scraping done and a cytological report that I just got back today- TL;DR it's looking like cancer:
"Site or Source:
Lateral thoracic lesion
Microscopic Description:
The slides are moderately cellular and have captured variably sized clusters of slightly cuboidal (epithelial) cells occasionally exfoliating with a scant amount of magenta mucinous extracellular material. The cells show modest cohesion and contain moderate amounts of basophilic cytoplasm, commonly with a light sprinkling of a very fine magenta granules. There nuclear to cytoplasmic ratio is moderate to high, and nuclei are round/ovoid to irregular with smooth chromatin and usually inapparent nucleoli. There is nuclear molding present in some clusters and anisokaryosis of approximately 2.5X. Erythrocytes are rare in the background.
Microscopic Interpretation:
FAVOUR EPITHELIAL TUMOR, See comment
Comment:
There is no evidence of inflammation, or any fungal agents found on cytology. Instead I am seeing a proliferation of modestly cohesive cells which I am interpreting as epithelial, and most likely neoplastic. I am not finding much literature regarding axolotl neoplasia, but epithelioma and neuroepithelioma are recognized in this species. The cells in question contain cytoplasmic granules resembling mast cells, and although mast cell tumor is also reported in axolotls, I do not believe the cells are mast cells based on the degree of cohesion. I considered whether this could be a regenerative blastema, but presumably the patient is not missing any limbs? Overall based on this sampling I suspect a neoplastic rather than infectious process; histopathology can be advised, if possible, and I would be interested in hearing of any follow-up information for this patient"
My vet is away until the 1st, so I'm just going to hang tight and do everything I can to minimize stress until then. He's pretty confident he will be able to treat it, thankfully. When he gets back we will do a biopsy just to get a 100% confirmation of what we're dealing with, and then formulate a plan from there.
Luckily lavender doesn't appear to be ill and is in good spirits despite being caught daily for baths and swabs. Mama mia this is an ordeal