Hi, i have a male and female together who recently became parents and i too have been thinking of this. I remember reading an article, that was talking about how stressful it is for the female laying the eggs, sometimes the female spends more than 24 hours laying eggs, so that must be stressful, so i would say overbreeding the one female, it can't be good for her, But, being her owner i think you would know if she is in good health, and if you take good care of them, regular feeding routine and good water quality and stable water temperature, as these are probably the most stressful to an axolotl if they are incorrect. So maybe if your axolotls are in perfect shape and good conditions then maybe they are good to keep breeding, especially if you can manage to keep/sell/trade give away the eggs, as it would be a shame to keep them breeding just to then cull the eggs. Its not an answer to your question, just a view and an opinion, hope it helps.